Steven Brem, MD joins the Department of Neurosurgery at Penn Medicine as Professor of Neurosurgery, Chief of Surgical Neuro-oncology and Co-Director of the Penn Brain Tumor Center.
Dr. Brem received his medical degree from Harvard Medical School. He completed his internship in surgery, and residency in neurosurgery, at Massachusetts General Hospital. Dr. Brem received additional training at the National Cancer Institute, and completed a neurosurgical fellowship at New York Hospital-Cornell Medical Center, as well as advanced training in stereotactic radiosurgery at UCLA School of Medicine.
Dr. Brem has devoted his career to optimizing outcomes for patients with brain tumors. He specializes in innovative, minimally invasive surgery for complex benign and malignant brain tumors, including meningiomas, acoustic neuromas, gliomas (glioblastomas), and brain metastases.
Dr. Brem has extensive experience, having performed more than 3,500 brain tumor surgeries. In addition, he chaired the NCCN committee that developed national guidelines for the state-of-the art treatment of a variety of brain tumors.
Dr. Brem’s research interests include the discovery and translation to the clinical arena of novel inhibitors of angiogenesis and glioma invasion. As one of the pioneers of anti-angiogenesis research, Dr. Brem was a co-founder of the NCI-sponsored clinical trials consortium, ABTC (NABTT), of which the University of Pennsylvania is an active member.
Dr. Brem has participated in more than 100 clinical trials centered on novel approaches for brain tumor therapy, including vaccine therapy; gene therapy; focused radiation therapy devices; molecular-targeted therapy; electrical fields; implantable chemowafers, and genomic ‘signatures’.
Dr. Brem sees patients at the Hospital of the University of Pennsylvania. To schedule an appointment with Dr. Brem, please call 800-789-PENN (7366) or
request an appointment online.